Ridge, Perry

Biology

Email: 2rgtt{0tkfigBd{w0gfw  (Email Form)

4126  LSB
Provo, UT 84602
(801) 422-7564

Assistant Professor

 Teaching Interests
Bioinformatics, Genetics, Genomics
 Research Interests
Bioinformatics, Computational Biology, Genetics
 Memberships
  • International Society for Computational Biology, 2013-Present
  • Alzheimer's Association, 2012-Present
  • American Society of Human Genetics, 2010-Present
 Courses Taught

Fall 2016
  • BIO 165: Introduction to Bioinformatics Section 001, 002
  • BIO 494R: Mentored Research Section 016
  • BIO 559R: Adv Topics Ecology & Evolution Section 003
Summer 2016
  • BIO 559R: Adv Topics Ecology & Evolution Section 004
Spring 2016
  • BIO 494R: Mentored Research Section 020
Winter 2016
  • BIO 165: Introduction to Bioinformatics Section 001, 002
  • BIO 494R: Mentored Research Section 017
  • BIO 559R: Adv Topics Ecology & Evolution Section 003

Selected Publications

Journal Articles

Gardner SG, Miller JB, Dean T, Robinson T, Erickson M, Ridge PG, McCleary WR. 2015. Genetic analysis, structural modeling, and direct couple analysis suggest a mechanism for phosphate signaling in Escherichia coli. BMC Genetics. 16(Suppl 2). <website> doi:10.1186/1471-2156-16-S2-S2

Lythgoe C, Perkes A, Peterson M, Schmutz C, Leary M, Ebbert MT, Ridge PG, Norton MC, Tschanz JT, Munger RG, et al. 2015. Population-based analysis of cholesteryl ester transfer protein identifies association between I405V and cognitive decline: the Cache County Study. Neurobiology of aging. 36(1):547.e1-3.  doi:10.1016/j.neurobiolaging.2014.08.022

Kauwe JS, Bailey MH, Ridge PG, Perry R, Wadsworth ME, Hoyt KL, Staley LA, Karch CM, Harari O, Cruchaga C, et al. 2014. Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation. PLoS genetics. 10(10):e1004758.  doi:10.1371/journal.pgen.1004758

Cruchaga C, Karch CM, Jin SC, Benitez BA, Cai Y, Guerreiro R, Harari O, Norton J, Budde J, Bertelsen S, et al. 2014. Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease. Nature. 505(7484):550-4.  doi:10.1038/nature12825

Ridge PG, Maxwell TJ, Foutz SJ, Bailey MH, Corcoran CD, Tschanz JT, Norton MC, Munger RG, O'Brien E, Kerber RA, et al. 2014. Mitochondrial genomic variation associated with higher mitochondrial copy number: the Cache County Study on Memory Health and Aging. BMC bioinformatics. 15 Suppl 7:S6.  doi:10.1186/1471-2105-15-S7-S6

Sharp AR, Ridge PG, Bailey MH, Boehme KL, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Kauwe JS. 2014. Population substructure in Cache County, Utah: the Cache County study. BMC bioinformatics. 15 Suppl 7:S8.  doi:10.1186/1471-2105-15-S7-S8

Ebbert MT, Wadsworth ME, Boehme KL, Hoyt KL, Sharp AR, O'Fallon BD, Kauwe JS, Ridge PG. 2014. Variant Tool Chest: an improved tool to analyze and manipulate variant call format (VCF) files. BMC bioinformatics. 15 Suppl 7:S12.  doi:10.1186/1471-2105-15-S7-S12

Ridge PG, Mukherjee S, Crane PK, Kauwe JS. 2013. Alzheimer's disease: analyzing the missing heritability. PLoS One. 8(11:e79771).  doi:10.1371/journal.pone.0079771

Chen K, Coonrod EM, Kumanovics A, Franks ZF, Durtschi JD, Margraf RL, Wu W, Heikal NM, Augustine NH, Ridge PG, et al. 2013. Germline Mutations in NFKB2 Implicate the Noncanonical NF-ë¼B Pathway in the Pathogenesis of Common Variable Immunodeficiency. Am. J. Hum. Genet.

Kauwe JS, Ridge PG, Foster NL, Cannon-Albright LA. 2013. Strong evidence for a genetic contribution to late-onset Alzheimer’s disease mortality: a population-based study. PLoS ONE. 8(10):e77087.  doi:10.1371/journal.pone.007087

Ridge PG, Koop A, Maxwell TJ, Bailey MH, Swerdlow RH, Kauwe JS, Honea RA. 2013. Mitochondrial haplotypes associated with biomarkers for Alzheimer’s disease. PLoS ONE. 8(9):e74158.  doi:10.1371/journal.pone.0074158

Ebbert MT, Ridge PG, Wilson AR, Sharp AR, Bailey M, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Kauwe JS. 2013. Population-based Analysis of Alzheimer’s Disease Risk Alleles Implicates Genetic Interactions. Biol. Psychiatry.  doi:10.1016/j.biopsych.2013.07.008

Ridge PG, Ebbert MT, Kauwe JS. 2013. Genetics of Alzheimer’s disease. Biomed Res Int. 2013:254954.  doi:10.1155/2013/254954

Conference Proceedings

Seeley M, Clement MJ, Giraud-Carrier CG, Snell QO, Bodily P, Fujimoto S, Kauwe JS, Ridge PG. 2014. A Structured Approach to Ensemble Learning for Alzheimer’s Disease Prediction. New York, NY, USA: ACM. <website> doi:10.1145/2649387.2660797

Bodily PM, Clement MJ, Snell QO, Fujimoto S, Ridge PG. 2014. Haplotype-centered Mapping for Improved Alignments and Genetic Association Studies. New York, NY, USA: ACM. <website> doi:10.1145/2649387.2649435

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