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David A. McClellan Biology Email: David_McClellan@byu.edu 699 WIDB Assistant Professor
Postdoctoral Ecperience:
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Theoretical aspects of protein and DNA molecular evolution. This includes mathematical and statistical modeling, software and other methodology development, and empirical analysis of protein-coding gene sequences. |
| Selected Publications |
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Articles Porter, M. L., T. Cronin, D. A. McClellan, and K. A. Crandall. "Molecular characterization of crustacean visual pigments and the evolution of pancrustacean opsins." Molecular Biology and Evolution. 24 (2007): 253-268. Perez-Losada, M., R. G. Christensen, D. A. McClellan, B. J. Adams, R. P. Viscidi, and K. A. Crandall. "Comparing phylogenetic codivergence between polyomaviruses and their hosts." Journal of Virology. 80 (2006): 5663-5669. Ebbert, M. T. W., T. D. O'Connor, W. A. Beckstead, M. J. Clement, and D. A. McClellan. "Pharmacogenomics: Analyzing SNPs in the CYP2D6 gene using amino acid properties." Proceedings of the Biotechnology and Bioinformatics Symposium. 3 (2006): 1-5. Baer, K. and D. A. McClellan. "Molecular coevolution of the vertebrate cytochrome c1 and Rieske iron sulfer proteins in the cytochrome bc1 complex." Proceedings of the Biotechnology and Bioinformatics Symposium. 3 (2006): 10-18. Chamala, S., W. A. Beckstead, M. J. Rowe, and D. A. McClellan. "Evolutionary selective pressure on three mitochondrial SNPs is consistent with their influence on metabolic efficiency in Pima Indians." Proceedings of the Biotechnology and Bioinformatics Symposium. 3 (2006): 35-44. Smith, R. L., S. A. Loughmiller, and D. A. McClellan. "Analysis of the effects of positive selection on physicochemical properties in the nicotinic acetylcholine receptor and associated structural implications." Proceedings of the Biotechnology and Bioinformatics Symposium. 3 (2006): 112-115. Porter, M. L., T. W. Cronin, D. A. McClellan, and K. A. Crandall. "The molecular evolution of invertebrate opsins." Investigative Ophthalmology & Visual Science. 47.E-Abstract (2006): 3748. A. C. Edmondson, D. Song, L. A. Alvarez, M. K. Wall, D. Almond, DAVID A. McCLELLAN, A. Maxwell, and B. L. Nielsen. "Characterization of an Arabidopsis thaliana mitochondrial-targeted single-stranded DNA binding protein." Molecular and General Genomics. 273 (2005): 115-122. DAVID A. McCLELLAN, J. L. Moss, E. J. Palfreyman, M. J. Smith, R. G. Christensen, and J. K. Sailsbery. "Physicochemical evolution and molecular adaptation of the cetacean cytochrome b protein." Molecular Biology and Evolution. 22 (2005): 437-455. McClellan, D. A., D. F. Whiting, R. G. Christensen, and J. K. Sailsbery. "Genetic codes as evolutionary filters: Subtle differences in the structures of genetic codes result in significant differences in patterns of nucleotide substitution." Journal of Theoretical Biology. 226:393-400 (2004). Wooley, S., M. Smith, J. Johnson, D. A. McClellan, K. A. Crandall. "Tree SAAP: Selection on Amino Acid Properties using phylogenetic trees." Bioinformatics. 19 (2003): 671-672. DAVID A. McCLELLAN. "Detecting Lehi's genetic signature." FARMS Review. 15 (2003): 35-90. McClellan, D. A. and K. G. McCracken. "Estimating the influence of selection on the variable amino acid sites of the cytochrome b protein functional domains." Molecular Biology and Evolution. 18 (2001): 917-925. McClellan, D. A. "The codon-degeneracy model of molecular evolution." Journal of Molecular Evolution. 50 (2000): 131-140. McClellan, D. A. "The phylogenetic utility of the codon-degeneracy model." Journal of Molecular Evolution. 51 (2000): 185-193. McCracken, K. G., J. Harshman, D. A. McClellan, and A. D. Afton. "Data set incongruence and correlated character evolution: an example of functional convergence in the hind-limbs of stifftail diving ducks." Systematic Biology. 48 (1999): 36-68. Books M. Perez-Losada, DAVID A. McCLELLAN, R. G. Christensen, R. P. Viscidi, and K. A. Crandall. Phylogenomics and molecular evolution of polyomaviruses. In: Polyomavirus and Human Diseases. Ed. N. Ahsan. 1st ed. Georgetown, Texas: Landes Bioscience, Mar. 2005. |
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