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Jeff G Edwards Physiology & Developmental Biology Email: jeffrey_edwards@byu.edu 455 WIDB Assistant Professor Office Hours: T, Th 12-1 |
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| Research |
My lab studies the mechanisms mediating learning and memory that occur based on responses to our environment, which are caused by synaptic plasticity or in other words changes in synapse activity or structure. The goal of the lab is to identify the mechanisms and signaling pathways causing different forms of plasticity in the hippocampus, the structure involved in spatial and declarative (fact) memory formation, and in other regions of the brain. We hope that by studying what mediates plasticity within different cell types of the hippocampus we will not only better understand normal hippocampal function, but what occurs to alter function in disease states such as Alzheimer's disease and epilepsy. |
| Selected Publications |
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Articles Gibson HE, Edwards JG, Page RS, Van Hook MJ, Kauer JA. "TRPV1 Channels Mediate Long-Term Depression at Synapses on Hippocampal Interneurons." Neuron. 57.5 (2008): 746-759. <website> Wang Z, Edwards JG, Riley N, Provance DW Jr, Karcher R, Li XD, Davison IG, Ikebe M, Mercer JA, Kauer JA, Ehlers MD. "Myosin Vb mobilizes recycling endosomes and AMPA receptors for postsynaptic plasticity." Cell. 135.3 (2008): 535-548. <website> T. JENSEN, D. BENNION, J. COUCH, M. CASTLE, S. DANIEL, *J. G. EDWARDS;. "TRPV1 modulation in the hippocampus." Program No. 737.7. 2008 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience. Online. Nov. 2008. <website> Edwards JG, Greig A, Sakata Y, Elkin D, Michel WC. "Cholinergic innervation of the zebrafish olfactory bulb." Journal of Comparative Neurology. 504.6 (2007): 631-645. <website> Park M, Penick EC, Edwards JG, Kauer JA, and Ehlers MD. "Recycling Endosomes Supply AMPA Receptors for LTP." Science. 305.5692 (2004): 1972-1975. <website> Edwards JG and Michel WC. "Pharmacological characterization of ionotropic glutamate receptors within the zebrafish olfactory bulb." Neuroscience. 122.4 (2003): 1037-1047. Edwards JG and Odell WD. "Partial characterization of chorionic gonadotropin-like binding sites from the bacteria Xanthomonas maltophilia." Experimental Biology and Medicine. 28.8 (2003): 926-934. Edwards JG and Michel WC. "Odor-stimulated glutamatergic neurotransmission in the zebrafish olfactory bulb." Journal of Comparative Neurology. 454.3 (2002): 294-309. |
| Experience |
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Professional
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| Awards |
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| Courses Taught |
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PDBIO 568
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Biophysics
NEURO 480 : Advanced Neuroscience PDBIO 650R : Sel Top PDBio/Neuro PDBIO 305 : Human Physiology (with lab) PDBIO 494R : Undergraduate Research PDBIO 495R : Adv Undgraduate Research NEURO 449R : Neuro Research Experience PDBIO 601 : Cell and Molecular Physiology (Graduate course) PDBIO 649R : Laboratory Research PDBIO 550R : Advanced Topics PDBIO 349R : PDBio Teach Sem |