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Allan M. Judd

Personal Information

Allan M. Judd
Physiology & Developmental Biology
Email: Allan_Judd@byu.edu

585 WIDB
Provo, UT 84602
(801) 422-3179

Professor

 Education
  • PhD , Physiology , West Virginia University , 1982
  • MS , Zoology , BYU , 1978
  • BS , Chemistry , BYU , 1973
 Research

Interactions between the immune and endocrine systems with emphases on the mechanism of interleukin-6 stimulation of cortisol release from the adrenal gland.

 Selected Publications

Articles

A.M. Woods, C.J. McIlmoil, E.N. Rankin, A.A. Packer, J.C. Stevens, J.A. Macievic, A.B. Brown, J.P. Porter, A.M. Judd.  "Leukemia inhibitory factor protein and receptors are expressed in the bovine adrenal cortex and increase cortisol and decrease adrenal androgen release."  Domest Anim Endocrinol.  35.2 (2008): 217-230. 

A.L. Heiner, E. Gibbons, J.L. Fairbourn, L.J. Gonzalez, C.O McLemore, T.J. Bueseke, A.M. Judd, J.D. Bell.  "Effects of cholesterol on physical properties of human erythrocyte membranes:impact on susceptibility to hydrolysis by secretory phospholipse A2."  Biophysical J.  94.4 (2008): 3084-3093. 

R.W. Bailey, E. Gibbons, L. Robertson. T.T. Nguyen, J. Nelson, A.M. Judd, J.D. Bell.  "Biphysical changes in the plasma membrane during glucocorticoid-stimulated apoptosis promote hydrolysis by secretory pholipase A2."  Biophysical Society 52nt Annual Meeting.  Jan. 2008. 

E.D. Olson, T.T. Nguyen, A.M. Judd, J.D. Bell.  "Relationship between membrane physical properties and secretory phospholipase A2 hydrolysis kinetics in S49 cells during ionophore-induced apoptosis."  Biophysical Society 52nd Annual Meeting.  Jan. 2008. 

R.W. Bailey, E. D. Olson, M. P. Vu, T. J. Brueseke, L. Robertson, K. H. Parker, A M. Judd, John D. Bell.  "Application of Membrane Biophysics to Cell Physiology: Mechanisms by which Apoptotic Membranes Become Susceptible to Secretory Phospholipase A2."  Biophysical Society 51st Annual Meeting.  Jan. 2007. 

S.A. McIlmoil, J. Strickland, J.P. Porter, S.N. Sudweeks, and A.M. Judd.  "Interleukin-6 inhibition of bovine adrenal androgen release involves suppresion of steroiogenic enzymes and SF-1 expression and augmentation of DAX-1 expression."  89th Annual Meeting of the Endocrine Society.  June 2007. 

B.D. Powell, S.A. McIlmoil, J. Strickland, and A.M. Judd.  "The human adrenal cell line H295R expresses micro inhibitory RNAs that may be involved in the regulation of steroidogenesis."  89th Annual Meeting of the Endocrine Society.  June 2007. 

J. Strickland, S.A. McIlmoil, S. J. McShane, J.L. Eliason, and A.M. Judd.  "Interleukin-6 may increase steroidogenic acute regulatory protein expression in human adrenal cell line H295R through activation of JAK/STAT pathway."  89th Annual Meeting of the Endocrine Society.  Apr. 2007. 

R.W. Bailey, E.D. Olson, M.P. Vu, T.J. Brueseke, L. Robertson, R.E. Christensen, K.H. Parker, A.M. Judd, and J.D. Bell.  "Relationship between Membrane Physical Properties and Secretory Phospholipase A2 Hydrolysis Kinetics in S49 Cells during Ionophore-Induced Apoptosis."  Biophys. J.  93 (2007): 2350-2362. 

A.M. Woods and A.M. Judd.  "Interleukin-4 increases cortisol release and decreases adrenal androgen release from bovine adrenal cells."  Domest Anim Endocrinol.  34.4 (2007): 372-382. 

S.A. McIlmoil, D. Maulouf , J. Strickland, B. D. Powell, S. J. McIntyre R.A. Castro, J.P. Porter, A.M. Judd.  "Induction of mRNA expression for adrenal steroidogenic enzymes by interleukin-6."  88th Annual Meeting of the Endocrine Society.  June 2006. 

R.W. Bailey, E. D. Olson, M. P. Vu, T. J. Brueseke, L. Robertson, K. H. Parker, A M. Judd, John D. Bell.  "Application of Membrane Biophysics to Cell Physiology: Mechanisms by which Apoptotic Membranes Become Susceptible to Secretory Phospholipase A2."  Biophysical Society 51st Annual Meeting.  Dec. 2006. 

Jensen, L.B., Burgess, N.K., Gonda, D.D., Spencer, E., Wilson-Ashworth, H.A., Driscoll, E., Vu, M.P, Fairbourn, J.L., Judd, A.M., and Bell, J.D.  "Mechanism governing the level of susceptibility of erythrocyte membranes to secretory phospholipase A2."  Biophysical Journal.  88 (2005): 2692-2705. 

J. Strickland, S.A. McIlmoil, R.A. Castro, J.P. Porter, A.M. Judd.  "Abstract: Interleukin-6 increases the expression of steroidogenic acute regulatory protein in bovine adrenal zona fasciculata fragments and H295R cell."  Program and Abstracts 87th Annual Meeting of The Endocrine Society.  Apr. 2005: 204. 

S.A. McIlmoil, R.A. Castro, J. Strickland, K.M. Taketa, J.P. Porter, A.M. Judd.  "Abstract: A possible role of the nuclear factors AP-1, steroidogenic factor-1, and DAX-1 in IL-6 stimulation of cortisol secretion."  Program and Abstracts 87th Annual Meeting of The Endocrine Society.  Apr. 2005: 204. 

Vest, R.S., L.R. Gonzales, S.A. Permann, E. Spencer, L.D. Hansen, A.M. Judd, J.D. Bell.  "Divalent Cations Increase Lipid Order in Erythrocytes and Susceptibility to Secretory Phospholipase A2."  Biophy. J.  86 (2004): 2251-2260. 

Wilson-Ashworth HA, A.M. Judd, R.M. Law, B.D. Freestone, S. Taylor, M.K. Mizukawa, K.R. Cromar, S. Sudweeks, and J.D. Bell.  "Formation of transient non-protein calcium pores by lysophospholipids in S49 lymphoma cells."  J. Membr. Biol.  200 (2004): 25-33. 

Jensen, L.B., H.A. Wilson-Ashworth, A.M. Judd, and J.D. Bell.  "Quantification of the absorption of secretory phospholipase A2 to cell membranes and relationship to it mechanism of action."  Biophys. J.  86 (2004): 377a. 

Taketa, K., A.J. Smith, J. McMullin, E. Nunez, G.C. Oliveira, J.P. Porter, and A.M. Judd.  "Toll-like receptor 4, CD-14, and toll-like receptor 2 are expressed in H295R adrenocortical cells and the rat adrenal cortex."  86th Annual Meeting of the Endocrine Society abstracts.  June 2004. 

Judd, A.M., K.B. Best, K. Christensen, G.M. Rodgers, and J.D. Bell.  "Alterations in sensitivity to calcium and enzymatic hydrolysis of membranes from sickle cell disease and trait erythrocytes."  Am. J. Hematol.  72 (2003): 162-169. 

Best, K.B., A.J. Ohran, A.C. Hawes, T.L. Hazlett, E. Gratton, A.M. Judd, and J.D. Bell.  "Relationship between erythrocyte membrane phase properties and susceptibility to secretory phospholipase A2."  Biochemistry.  41 (2002): 13982-13988. 

Call, G.B., O.F. Husein, C.J. McIlmoil, A. Adams, R.A. Heckmann, and A.M. Judd.  "Bovine adrenal cells secrete interleukin-6 and tumor necrosis factor in vitro."  General and Comparative Endocrinology.  118 (2000): 249-261. 

# Barney, M., G.B. Call, C.J. McIlmoil, O.F. Husein, A. Adams, A.G. Balls, G.K. Oliveira, E. Miner, T.A. Richards, B.K. Crawford, R.A. Heckmann, J.D. Bell, and A.M. Judd.  "Stimulation by interleukin-6 and inhibition by tumor necrosis factor of cortisol release from bovine adrenal zona fasciculata cells through their receptors."  Endocrine.  13 (2000): 369-377. 

Wilson, H.A., J.B. Waldrip, K.H. Nielson, A.M. Judd, S.K. Han, W. Cho, P.J.  "Mechanism by which elevated intracellular calcium induces S49 cell membranes to become susceptible to the action of secretory phospholipase A2."  Journal of Biological Chemistry.  274 (1999): 11494-11504. 

Books

Judd, A.M., G.B. Call, M. Barney, C.J. McIlmoil, A.G. Balls, and G.K. Oliveira.  "Possible function of IL-6 and TNF as intraadrenal factors in the regulation of adrenal steroid secretion."  Annals New York Academy Of Sciences.  2000.  Vol. 917. 

 Experience

General

  • Associate Professor , Department of Zoology, BYU , 1997-2002
  • Assistant Professor , Dept. Zoology, BYU , 1991-1997
  • Research Assistant Professor , University of Virginia, Dept. Medicine , 1986-1991
  • Research Associate , University of Virginia, Dept. Medicine , 1985-1986
  • Postdoctoral fellowship , University of Virginia, Dept. Medicine , 1981-1985

Professional

  • Professor , Physiology and Developmental Biology , 2006-Present
  • Associate Professor , Department of Physiology and Developmental Biology , 2002-2006

 Awards
  • College Outstanding Citizenship Award , College of Biology and Agriculture , 2005
  • Outstanding Faculty , Department of Physiology and Developmental Biology, BYU , 2002
  • College Outstanding Advisor , College of Biology and Agriculture, BYU , 2000
  • Four-year competitive graduate student scholarship , West Virginia University , 1978
  • Graduated with honors , Dept. of Chemistry, BYU , 1973
  • Full Scholarship , Dept. of Chemistry, BYU , 1969
 Courses Taught
PDBio 362 Advanced Physiology. Spring term.
PDBio 363 Advanced Physiology Laboratory. Spring term.
PDBio 365 Pathophysiology. Fall semester.
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