J.R. Tolman, E.D. Lephart, K.D.R. Setchell, D.L. Eggett, M.J. Christensen.  "Timing of Supplementation of Selenium and Isoflavones Determines Prostate Cancer Risk Factor Reduction in Rats."  Nutriton and Metabolism.  5.0 (2008): 1-12. 

R.L. Legg, J.R. Tolman, C.T. Lovinger, E.D. Lephart, K.D. Setchell, M.J. Christensen.  "Diets High in Selenium and Isoflavones Decrease Androgen-Regulated Gene Expression in Health Rat Dorsolateral Prostate."  Reproductive Biology & Endocrinology.  6.0 (2008): 1-14. 

K. Fabick, C. Blake, J.P. Porter, K.D.R. Setchell, E.D. Lephart.  "Positive Benefits of Consuming Soy-Derived Isoflavones on Body Weight Gain, Adipose Tissue Deposition and Preliminary Cardiovascular Parameters Examined in a Ovariectomized Rat Model."  Experimental Biology 2007.  34 (2007): W 135. 

R.L. Leff, J.R. Tolman, C.T. Lovinger, E.D. Lephart, K.D.R. Setchell, M.J. Christensen.  "Selenium, Isoflavones, and AR-Regulated Genes in Rat Prostate."  Experimental Biology 2007.  34 (2007): T-243. 

M. Robins, E.D. Lephart, G.M. Alder.  "Improved Synthesis of Cladribine."  Bio 2007.  12 (2007): P-8. 

G.M. Alder, M. Andrus, E.D. Lephart.  "Novel Trans-Resveratrol Esters and the "French Paradox"-Applications in Health and Disease."  Bio 2007.  12 (2007): P12. 

G.M. Alder, E.D. Lephart.  "Use of Equol for Treating Skin, Hair, Brain and Prostate Health and Obesity/Weight Control."  Bio 2007.  12 (2007): P-14. 

C. Blake, K. Fabick, E.D. Lephart.  "Long-Evans Newborn Male Rats, Prenatally-Treated with Equol Display Variations in Body Weight and External Gential Development."  AAPS.  11 (2007): P-573. 

L. Bu, E.D. Lephart.  "AVPV Neurons Containing Estrogen Receptor-Beta in Adult Male Rats are Influenced by Soy Isoflavones."  BMC Neuroscience.  8.13 (2007): 1-12. 

L. Bu, E.D. Lephart.  "Regulatory Behavior and Skin Temperature in Mid-Aged Male Rats on Three Different Isoflavone-Containing Diets."  Journal of Medicinal Food.  9.4 (2006): 567-571. 

Edwin D. Lephart.  "Equol: A Unique Anti-Androgenic Isoflavone Metabolite Stimulates Collagen (I & III), Elastin and Human Fibroblast Proliferation and Inhibits MMPs and Elastase in 3-D Cultures via FACS Analysis."  American Academy of Dermatology.  41.1 (2006): P1111. 

E.D. Lephart, B. Nance and P. Nibley.  "Equol: Does Not Alter Adult Hypothalamic Brain Structures (Volumetric SDN and AVPV Parameters) That Are Sensitive To Steroid Hormone Influences."  American Association of Pharmaceutical Scientists.  10.10 (2006): W 321. 

E.D. Lephart, J. Little, L. Bu, P. Nibley, B. Nance, K. Setchell.  "Equol is More Potent Compared to Genistein in Decreasing Anxiety Levels via Pre- and Early Postnatal Treatment in Male Rat Offspring Tested as Adults."  American Association of Pharmaceutical Scientists.  10.3 (2006): W322. 

E.D. Lephart, L. Bu, C.D. Foradori, T.D. Lund, K.D.R. Setchell.  "5Alpha-Dihydrotestosterone and Anxiety-Related Behaviors Are Decreased In Adult Rats by Equol: A Major Isoflavone Metabolite."  American Association of Pharmaceutical Scientists.  10.3 (2006): W 323. 

E.D. Lephart, P. Nibley, B. Nance, T.D. Lund.  "Equol: Anti-depressant Actions in Mid-Aged Female Rats."  American Association of Pharmaceutical Scientists.  10.3 (2006): W324. 

ED Lephart, TD Lund, RJ Handa, KDR Setchell.  "Anti-Aging Effects of Equol: A Unique Anti-Androgenic Isoflavone Metabolite and Its Influence in Stimulating Collagen Deposition in Human Dermal Monolayer Fibroblasts."  American Academy of Dermatology.  134.2 (2005): 105. 

ED Lephart.  "The Influence of Equol on Androgen Levels, Prostate and Skin Tail Temperature in Male Rats."  Experimental Biology.  86.1 (2005): 129. 

L Bu, ED Lephart.  "Estrogen Receptor beta Mediates Apoptosis in Adult Anteroventral Periventricular Nucleus (AVPV) by Consumption of Soy Isoflavones."  Society for Neuroscience.  24.1 (2005): 89. 

L Bu, ED Lephart.  "Effects of Dietary Phytoestrogens on Core Body Temperature during the Estrous Cycle and Pregnancy."  Brain Research Bulletin.  65.3 (2005): 219-223. 

ED Lephart, KDR Setchell, TD Lund.  "Phytoestrogens: Hormonal Action and Brain Plasticity."  Brain Research Bulletin.  65.3 (2005): 193-198. 

KDR Setchell, C Clerici, ED Lephart, SJ Cole, C Heenan, D Castellani, BE Wolfe, L Nechemias-Zimmer, NM Brown, TD Lund, RJ Handa.  "S-Equol, a potent ligand for estrogen receptor beta, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora."  American Journal Clinical Nutrition.  81.3 (2005): 1071-1079. 

L Bu, ED Lephart.  "Soy Isoflavones modulate the expression of BAD and neuron-specific beta III tubulin in male rat brain."  Neuroscience Letters.  385.3 (2005): 153-157. 

L Bu, KDR Setchell ED Lephart.  "Influences of Dietary Soy Isoflavones on Metabolism but Not Nociception and Stress Hormones Responses in Ovariectomized Female Rats."  Reproductive Biology & Endocrinology.  3.1 (2005): 58-electronic. 

Lund, T.D., D.J. Munson, M.E. Haldy, K.D.R. Setchell, E.D. Lephart, and R.J. Handa.  "Equol is a novel anti-androgen that inhibits prostate growth and hormone feedback."  Biology of Reproduction.  70 (2004): 1188-1195. 

Lund, T.D., D.J. Munson, H. Adlercreutz, R.J. Handa, and E.D. Lephart.  "Androgen receptor expression in the rat prostate is down-regulated by dietary phytoestrogens."  Reproductive Biology & Endrocinology.  2 (2004): 5. 

Lephart, E.D., J.P. Porter, T.D. Lund, L. Bu, K.D.R. Setchell, G. Ramoz, W.R. Crowley.  "Dietary isoflavones alter regulatory behaviors, metabolic hormones and neuroendocrine function in Long-Evans male rats."  Nutrition & Metabolism.  1 (2004): 16. 

Lephart, E.D., K.D.R. Setchell, R.J. Handa and T.D. Lund.  "Behavioral effects of endocrine-disrupting substances: phytoestrogens."  Institute Laboratory Animal Research (National Research Council of the National Academy (USA).  45 (2004): 443-454. 

Lephart, E.D., J.P. Porter, D.W. Hedges, T.D. Lund, and K.D.R. Setchell.  "Phytoestrogens: Implications in Neurovascular Research."  Current Neurovascular Research.  1 (2004): 455-464. 

Lund, T.D., K.D.R. Setchell, E.D. Lephart, and R.J. Handa.  "Unique endocrine properties of the phytoestrogen metabolite equol."  Recent Research Developments in Endocrinology.  4 (2004): 181-208. 

Hedges, D.W., C.M. Massari, D.L. Salyer, T.D. Lund, J.L. Hellewell, A.C. Johnson, E.D. Lephart.  "Duration of Transcranial Magnetic Stimulation (TMS) Effects on the Neuroendocrine Stress Response and Coping Behavior in Adult Male Rats."  Progress in Neuro-Psychopharmacology and Biological Psychiatry.  27 (2003): 633-638. 

Lephart, E.D., E. Galindo and L.H. Bu.  "Stress (HPA axis) and pain response in male rats exposed lifelong to high vs. low phytoestrogen diets."  Neuroscience Letters.  342 (2003): 65-68. 

Lephart, E.D., R.W. Rhees, K.D.R. Setchell, L.H.Bu and T.D. Lund.  "Estrogens & Phytoestrogens: Brain Plasticity of Sexually Dimorphic Brain Volumes."  Journal of Steroid Biochemistry and Molecular Biology.  85 (2003): 299-309. 

Lephart, E.D., D. Hedges.  "Dementia, Estrogen, and Diet: A Possible Role of Phytoestrogens (Isoflavones) in Alzheimers Disease, In: Focus on Alzheimers Disease Research."  Nova Scientific Publishers, Hauppage, NY.  2003. 

Lephart, E.D., T.D. West, K.S. Weber, R.W. Rhees, K.D.R. Setchell, H. Adlercreutz and T.D. Lund.  "Neurobehavioral Effects of Dietary Soy Phytoestrogens."  Neurotoxicology and Teratology.  24 (2002): 1-12. 

Hedges, D.W., D.L. Sawyer, B.J. Higginbotham, T.D. Lund, J.L. Hellewell, D. Ferguson and E.D. Lephart.  "Transcranial Magnetic Stimulation (TMS) effects on Testosterone, Prolactin, and Corticosterone in Adult Male Rats."  Biological Psychiatry.  51 (2002): 417-421. 

Lephart, E.D., S. B. Call, R.W. Rhees, N.A. Jacobson, K.S. Weber, J. Bledsoe and C. Teuscher.  "Neuroendocrine Regulation of Sexually Dimorphic Brain Structure and Associated Sexual Behavior in Male Rats is Genetically Controlled."  Biology of Reproduction.  64 (2001): 571-578. 

Weber, K.S., K.D.R. Stechell and E.D. Lephart.  "Maternal and Perinatal Brain Aromatase: Effects of Dietary Soy Phytoestrogens."  Developmental Brain Research.  126 (2001): 217-221. 

Salyer, D.L., T.D. Lund, D.E. Fleming, E.D. Lephart and T.L. Horvath.  "Sexual Dimorphism and Aromatase in the Rat Retina."  Developmental Brain Research.  126 (2001): 131-136. 

Rhees, R.W., E.D. Lephart and D. Eliason.  "Effects of maternal separation during early postnatal development on male sexual behavior and female reproductive function."  Behavioral Brain Research.  123 (2001): 1-10. 

Weber, K.S., K.D.R. Setchell, D.M. Stocco and E.D. Lephart.  "Dietary Soy Phytoestrogens Decrease Testosterone Levels and Prostate Weight, Without Altering LH, Prostate 5a-Reductase or Testicular StAR Levels in Adult Male Sprague-Dawley Rats."  Journal of Endocrinology.  170 (2001): 591-599. 

Stuart, E.B., J.M. Thompson, R.W. Rhess and E.D. Lephart.  "Steroid Hormone Influence on Brain Calbindin-D28K in Male Prepubertal and Ovariectomized Rats."  Developmental Brain Research.  129 (2001): 125-133. 

Lund, T.D., R.W. Rhees, K.D.R. Setchell and E.D. Lephart.  "Altered Sexually Dimorphic Nucleus of the Preoptic Area (SDN-POA) Volumes in Adult Long-Evans Rats by Dietary Soy Phytoestrogens."  Brain Research.  914 (2001): 92-99. 

Lund, T.D., and E.D. Lephart.  "Dietary Soy Phytoestrogens Produce Anxiolytic Effects in the Elevated Plus Maze."  Brain Research.  913 (2001): 180-184. 

Lephart, E.D., H. Adlercreutz, T.D. Lund.  "Dietary Soy Phytoestrogen Effects On Brain Structure and Aromatase in Long-Evans Rats."  NeuroReport.  12 (2001): 3451-3455. 

Lephart, E.D., T.D. Lund and T.A. Horvath.  "Brain Androgen and Progesterone Metabolizing Enzymes: Biosynthesis, Distribution and Function."  Brain Research Reviews.  37 (2001): 25-37. 

Lund, T.D., T.W. West, L.Y. Tian, D.L. Simmons, K.D.R. Setchell, H. Adlercreutz and E.D. Lephart.  "Visual Spatial Memory is Enhanced in Females (but not in males) by Dietary Soy Phytoestrogens."  BioMedical Central (BMC) Neuroscience.  3 (2001): 23-33. 

Lund, T.D. and E.D. Lephart.  "Manipulation of Prenatal Hormones and Dietary Phytoestrogens During Adulthood Alter the Sexually Dimorphic Expression of Visual Spatial Memory."  BioMedical Central (BMC) Neuroscience.  3 (2001): 34-40. 

Lephart, E.D., R.Ward Rhees, K.D.R. Setchell and T.D. Lund.  "Dietary Soy Phytoestrogens Alter Sexually Dimorphic Hypothalamic Nuclei in Adult Rats."  Experimental Biology.  2001. 

Lephart, E.D. and T.D. Lund.  "Dietary soy phytoestrogens produce anxiolytic effects in the elevated plus-maze."  Neurotoxicology & Teratology.  2001. 

Lephart, E.D., J.M. Thompson, K.D.R. Setchell, Adlercreutz and K.S. Weber.  "Dietary Soy-Phytoestrogens Decrease Brain Calcium-Binding Proteins But Do Not Alter Androgen Metabolizing Enzymes in Adult Rats."  Brain Research.  859 (2000): 123-131. 

Lund, T., D.L. Salyer, D.E. Fleming and E.D. Lephart.  "Pre- or Postnatal Testosterone and Flutamide Effects on Sexually Dimorphic Nuclei of the Rat Hypothalamus."  Developmental Brain Research.  120 (2000): 261-266. 

Mathias, L., R. W. Rhees, N.A. Jacobson and E.D. Lephart.  "Brain Aromatase in Control versus Castrated Norway Brown, Sprague-Dawley and Wistar Adult Rats."  Proceedings Society Experimental Biology Medicine.  221 (1999): 126-130. 

Weber, K.S., N.A. Jacobson, K.D. Setchell and E.D. Lephart.  "Brain Aromatase and 5a-Reductase, Regulatory Behaviors and Testosterone Levels in Adult Rats on Phytoestrogen Diets."  Proceedings Society Experimental Biology Medicine.  221 (1999): 131-135. 

Taylor, H., E.M. Quintero, A.M. Iacopino and E.D. Lephart.  "Phytoestrogens Alter Hypothalamic Calbindin-D28K Levels During Prenatal Development."  Developmental Brain Research.  114 (1999): 277-281. 

Rhees, R.W., H.N. Al-Saleh, E.W. Kinghorn, D.E. Fleming and E.D. Lephart.  "Relationship Between Sexual Behavior and Sexually Dimorphic Structures in the Anterior Hypothalamus in Control and Prenatally Stressed Male Rats."  Brain Research Bulletin.  50 (1999): 193-199. 

Lephart, E.D., and M.A. Watson.  "Effects of Early Postnatal Maternal Separation on Hypothalamic-Preoptic Area and Hippocampal Calbindin-D28K in Male and Female Infantile Rats."  Neuroscience Letters.  267 (1999): 41-44. 

ED Lephart.  "The Influence of Human Infant Formulas Containing Isoflavones on Brain Aromatase Activity in Rats."  Journal of Medicinal Food.  33.4 (1999): 201-204. 

Stuart, E., and E.D. Lephart.  "Dimorphic Expression of Medial Basal Hypothalamic-Preoptic Area Calbindin-D(28K) mRNA During Perinatal Development and Adult Brain Tissue Distribution of Calbindin-D(28K) mRNA in Sprague-Dawley Rats."  Molecular Brain Research.  73 (1999): 60-67.