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John D Bell

Personal Information

John D Bell
Undergraduate Education
Email: john_bell@byu.edu

302A MSRB
Provo, UT 84602
(801) 422-3037

Professor
Dean

 Education
  • PhD , Physiology and Pharmacology , University of California, San Diego , 1987
  • BS , Zoology , Brigham Young University , 1982
 Research

Membrane biophysics. Mechanism of action of secretory phospholipase A2.

 Selected Publications

Articles

Heiner, A.L., Gibbons, E., Fairbourn, J.L., Gonzalez, L.J., McLemore, C.O., Brueseke, T.J., Judd, A.M., and Bell, J.D.  "Effects of cholesterol on physical properties of human erythrocyte membranes: Impact on susceptibility to hydrolysis by secretory phospholipase A2."  Biophysical Journal.  94 (2008): 3088-3093. 

Stott, B.M., Vu, M.P., McLemore, C.O., Lund, M.S., Gibbons, E., Brueseke, T.J., Wilson-Ashworth, H.A., and Bell, J.D.  "Use of fluorescence to determine the effects of cholesterol on lipid behavior in sphingomyelin liposomes and erythrocyte membranes."  Journal of Lipid Research.  49 (2008): 1202-1215. 

Bailey, R.W., Olson, E.D., Vu, M.P., Brueseke, T.J., Robertson, L., Christensen, R.E., Parker, K.H., Judd, A.M., and Bell, J.D.  "Relationship between Membrane Physical Properties and Secretory Phospholipase A2 Hydrolysis Kinetics in S49 Cells during Ionophore-Induced Apoptosis."  Biophysical Journal.  93 (2007): 2350-2362. 

Kitchen, E., Reeve, S., Bell, J.D., Sudweeks, R.R., and Bradshaw, W.S.  "The development and application of affective assessment in an upper-level cell biology course."  Journal of Research in Science Teaching.  44 (2007): 1057-1087. 

Kitchen, E., King, S.H., Robison, D.F., Sudweeks, R.R., Bradshaw, W.S., and Bell, J.D.  "Rethinking exams and letter grades: how much can teachers delegate to students?."  Cell Biology Education: Life Science Education.  5 (2006): 270-280. 

Vest, R., Wallis, R., Jensen, L.B., Haws, A.C., Callister, J., Brimhall, B., Judd, A.M., and Bell, J.D.  "Use of steady-state laurdan fluorescence to detect changes in liquid ordered phases in human erythrocyte membranes."  Journal of Membrane Biology.  211 (2006): 15-25. 

Brueseke, T.J. and Bell, J.D.  "A new hat for an old enzyme: Waste management."  Biochimic et Biophysica Acta.  1761 (2006): 1270-1279. 

Yaworsky, D.C., Baker, B.Y., Bose, H.S., Best, K.B., Jensen, L.B., BELL, J.D., Baldwin, M.A., and Miller, W.L.  "pH-dependent interactions of the carboxyl-terminal helix of steroidogenic acute regulatory protein with synthetic membranes."  J. Biol. Chem.  280 (2005): 2045-2054. 

Jensen, L.B., Burgess, N.K., Gonda, D.D., Spencer, E., Wilson-Ashworth, H.A., Driscoll, E., Vu, M.P., Fairbourn, J.L., Judd, A.M., and BELL, J.D.  "Mechanisms Governing the Level of Susceptibility of Erythrocyte Membranes to Secretory Phospholipase A2."  Biophys. J.  88 (2005): 2692-2705. 

Vest, R.S., Gonzales, L.J., Permann, S.A., Spencer, E., Hansen, L.D., Judd, A.M., and Bell, J.D.  "Divalent Cations Increase Lipid Order in Erythrocytes and Susceptibility to Secretory Pospholipase A2."  Biophys. J.  86 (2004): 2251-2260. 

Wilson-Ashworth, H.A., Judd, A.M., Law, R.M., Freestone, B.D., Taylor, S., Mizukawa, M.K., Cromar, K.R., Sudweeks, S., and Bell, J.D.  "Formation of transient non-protein calcium pores by lysophospholipids in S49 Lymphoma cells."  J. Membr. Biol.  200 (2004): 25-33. 

Judd, A.M., Best, K.B., Christensen, K., Rodgers, G.M., and Bell, J.D.  "Alterations in sensitivity to calcium and enzymatic hydrolysis of membranes from sickle cell disease and trait erythrocytes."  Am. J. Hematol.  72 (2003): 162-169. 

Kitchen, E., Bell, J.D., Reeve, S., Sudweeks, R.R., and Bradshaw, W.S.  "Teaching Cell Biology in the Large Enrollment Classroom: Methods to Promote Analytical Thinking and Assessment of Their effectiveness."  Cell Biol. Ed.  2 (2003): 180-194. 

Bell, J.D., Sanchez, S.A., and Hazlett, T.L.  "Liposomes in the study of phospholipase A2 activity."  Methods Enzymol.  372 (2003): 19-48. 

Harris, F.M., Best, K.B., and Bell, J.D.  "Use of laurdan fluorescence intensity and polarization to distinguish between changes in membrane fluidity and phospholipid order."  Biochim. Biophys. Acta.  1565 (2002): 123-128. 

Christensen, K., Bose, H.S., Harris, F.M., Miller, W.L., and Bell, J.D.  "Binding of steroidogenic acute regulatory protein to synthetic membranes suggests an active molten globule."  Journal of Biological Chemistry.  276 (2001): 17044-17051. 

Harris, F.M., Smith, S.K., and Bell, J.D.  "Physical properties of erythrocyte ghosts that determine susceptibility to secretory phospholipase A2."  Journal of Biological Chemistry.  276 (2001): 22722-22731. 

Smith, S.K., Farnbach, A.R., Harris, F.M., Hawes, A.C., Jackson, L.R., Judd, A.M., Vest, R.S., Sanchez, S., and Bell, J.D.  "Mechanisms by which intracellular calcium induces susceptibility to secretory phospholipase A2 in human erythrocytes."  Journal of Biological Chemistry.  276 (2001): 22732-22741. 

Nielson, K.H., C.A. Olsen, D.V. Allred, K.L. ONeill, G.F. Burton, J.D. Bell.  "Susceptibility of S49 lymphoma cell membranes to hydrolysis by secretory phospholipase A2 during early phase of apoptosis."  Biochimica et Biophysica Acta.  1484 (2000): 163-174. 

Wilson, H.A., D.V. Allred, K.L. ONeill, J.D. Bell.  "Activities and interactions among phospholipases A2 during thapsigargin-induced S49 cell death."  Apoptosis.  5 (2000): 389-396. 

Barney, M., G.B. Call, C.J. Mcllmoil, O.F. Husein, A. Adams, A.G. Balls, G. Oliveira, E.C. Miner, T.A. Richards, B.K. Crawford, R.A. Heckmann, J.D. Bell, A.M. Judd.  "Stimulation by interleukin-6 and inhibition by tumor necrosis factor of cortisol release from bovine adrenal zona fasciculata cells through their receptors."  Endocrine.  13 (2000): 369-377. 

Wilson, H.A., J.B. Waldrip, K.H. Nielson, A.M. Judd, S.K. Han, W. Cho, P.J. Sims, J.D. Bell.  "Mechanisms by which elevated intracellular calcium induces S49 cell membranes to become susceptible to the action of secretory phospholipase A2."  Journal of Biological Chemistry.  274 (1999): 11494-11504. 

Books

Janssen, H.F., Skeen, N.P., Bell, J., and Bradshaw, W.  "Improving critical thinking skills in the medical professional with team-based learning."  Team-Based Learning for Health Professions Education.  Ed. L.K. Michaelsen, D.X. Parmelee, K.K. McMahon, and R.E. Levine.  Sterling, Virginia: Stylus Publishing, 2008. 

 Experience

General

  • Professor , Department of Physiology and Developmental Biology, BYU , 2002-Present
  • Associate Dean , College of Biology and Agriculture, BYU , 2001-Present
  • Chair , Department of Zoology, BYU , 1998-2001
  • Associate Professor , Department of Zoology, BYU , 1996-2002
  • Assistant Professor , BYU , 1990-1996
  • NRSA Postdoctoral Fellow , University of Virgina, Department of Pharmacology , 1987-1990

 Awards
  • Outstanding Faculty , Department of Physiology and Developmental Biology , 2008
  • Karl G. Maeser Distinguished Teaching Award , BYU , 1996
  • Outstanding Faculty, Department of Zoology , BYU , 1994
  • Young Scholar Award , BYU , 1993
  • National Service Research Award Individual Postdoctoral Fellowship , NIH award GM-11838 , 1988
  • Predoctoral fellowship in pharmacology/toxicology , Pharmaceutical Manufacturers Association Foundation , 1985
 Courses Taught
Biol 120 Science of Biology. Fall and Winter semesters.
Biology | Microbiology & Molecular Biology | Nutrition, Dietetics & Food Science | Physiology & Developmental Biology | Plant & Wildlife Sciences
Life Sciences Office | Office of Academic Advisement | Office of College Life
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