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John D Bell Undergraduate Education Email: john_bell@byu.edu 302A MSRB Professor
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| Education |
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| Research |
Membrane biophysics. Mechanism of action of secretory phospholipase A2. |
| Selected Publications |
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Articles Heiner, A.L., Gibbons, E., Fairbourn, J.L., Gonzalez, L.J., McLemore, C.O., Brueseke, T.J., Judd, A.M., and Bell, J.D. "Effects of cholesterol on physical properties of human erythrocyte membranes: Impact on susceptibility to hydrolysis by secretory phospholipase A2." Biophysical Journal. 94 (2008): 3088-3093. Stott, B.M., Vu, M.P., McLemore, C.O., Lund, M.S., Gibbons, E., Brueseke, T.J., Wilson-Ashworth, H.A., and Bell, J.D. "Use of fluorescence to determine the effects of cholesterol on lipid behavior in sphingomyelin liposomes and erythrocyte membranes." Journal of Lipid Research. 49 (2008): 1202-1215. Bailey, R.W., Olson, E.D., Vu, M.P., Brueseke, T.J., Robertson, L., Christensen, R.E., Parker, K.H., Judd, A.M., and Bell, J.D. "Relationship between Membrane Physical Properties and Secretory Phospholipase A2 Hydrolysis Kinetics in S49 Cells during Ionophore-Induced Apoptosis." Biophysical Journal. 93 (2007): 2350-2362. Kitchen, E., Reeve, S., Bell, J.D., Sudweeks, R.R., and Bradshaw, W.S. "The development and application of affective assessment in an upper-level cell biology course." Journal of Research in Science Teaching. 44 (2007): 1057-1087. Kitchen, E., King, S.H., Robison, D.F., Sudweeks, R.R., Bradshaw, W.S., and Bell, J.D. "Rethinking exams and letter grades: how much can teachers delegate to students?." Cell Biology Education: Life Science Education. 5 (2006): 270-280. Vest, R., Wallis, R., Jensen, L.B., Haws, A.C., Callister, J., Brimhall, B., Judd, A.M., and Bell, J.D. "Use of steady-state laurdan fluorescence to detect changes in liquid ordered phases in human erythrocyte membranes." Journal of Membrane Biology. 211 (2006): 15-25. Brueseke, T.J. and Bell, J.D. "A new hat for an old enzyme: Waste management." Biochimic et Biophysica Acta. 1761 (2006): 1270-1279. Yaworsky, D.C., Baker, B.Y., Bose, H.S., Best, K.B., Jensen, L.B., BELL, J.D., Baldwin, M.A., and Miller, W.L. "pH-dependent interactions of the carboxyl-terminal helix of steroidogenic acute regulatory protein with synthetic membranes." J. Biol. Chem. 280 (2005): 2045-2054. Jensen, L.B., Burgess, N.K., Gonda, D.D., Spencer, E., Wilson-Ashworth, H.A., Driscoll, E., Vu, M.P., Fairbourn, J.L., Judd, A.M., and BELL, J.D. "Mechanisms Governing the Level of Susceptibility of Erythrocyte Membranes to Secretory Phospholipase A2." Biophys. J. 88 (2005): 2692-2705. Vest, R.S., Gonzales, L.J., Permann, S.A., Spencer, E., Hansen, L.D., Judd, A.M., and Bell, J.D. "Divalent Cations Increase Lipid Order in Erythrocytes and Susceptibility to Secretory Pospholipase A2." Biophys. J. 86 (2004): 2251-2260. Wilson-Ashworth, H.A., Judd, A.M., Law, R.M., Freestone, B.D., Taylor, S., Mizukawa, M.K., Cromar, K.R., Sudweeks, S., and Bell, J.D. "Formation of transient non-protein calcium pores by lysophospholipids in S49 Lymphoma cells." J. Membr. Biol. 200 (2004): 25-33. Judd, A.M., Best, K.B., Christensen, K., Rodgers, G.M., and Bell, J.D. "Alterations in sensitivity to calcium and enzymatic hydrolysis of membranes from sickle cell disease and trait erythrocytes." Am. J. Hematol. 72 (2003): 162-169. Kitchen, E., Bell, J.D., Reeve, S., Sudweeks, R.R., and Bradshaw, W.S. "Teaching Cell Biology in the Large Enrollment Classroom: Methods to Promote Analytical Thinking and Assessment of Their effectiveness." Cell Biol. Ed. 2 (2003): 180-194. Bell, J.D., Sanchez, S.A., and Hazlett, T.L. "Liposomes in the study of phospholipase A2 activity." Methods Enzymol. 372 (2003): 19-48. Harris, F.M., Best, K.B., and Bell, J.D. "Use of laurdan fluorescence intensity and polarization to distinguish between changes in membrane fluidity and phospholipid order." Biochim. Biophys. Acta. 1565 (2002): 123-128. Christensen, K., Bose, H.S., Harris, F.M., Miller, W.L., and Bell, J.D. "Binding of steroidogenic acute regulatory protein to synthetic membranes suggests an active molten globule." Journal of Biological Chemistry. 276 (2001): 17044-17051. Harris, F.M., Smith, S.K., and Bell, J.D. "Physical properties of erythrocyte ghosts that determine susceptibility to secretory phospholipase A2." Journal of Biological Chemistry. 276 (2001): 22722-22731. Smith, S.K., Farnbach, A.R., Harris, F.M., Hawes, A.C., Jackson, L.R., Judd, A.M., Vest, R.S., Sanchez, S., and Bell, J.D. "Mechanisms by which intracellular calcium induces susceptibility to secretory phospholipase A2 in human erythrocytes." Journal of Biological Chemistry. 276 (2001): 22732-22741. Nielson, K.H., C.A. Olsen, D.V. Allred, K.L. ONeill, G.F. Burton, J.D. Bell. "Susceptibility of S49 lymphoma cell membranes to hydrolysis by secretory phospholipase A2 during early phase of apoptosis." Biochimica et Biophysica Acta. 1484 (2000): 163-174. Wilson, H.A., D.V. Allred, K.L. ONeill, J.D. Bell. "Activities and interactions among phospholipases A2 during thapsigargin-induced S49 cell death." Apoptosis. 5 (2000): 389-396. Barney, M., G.B. Call, C.J. Mcllmoil, O.F. Husein, A. Adams, A.G. Balls, G. Oliveira, E.C. Miner, T.A. Richards, B.K. Crawford, R.A. Heckmann, J.D. Bell, A.M. Judd. "Stimulation by interleukin-6 and inhibition by tumor necrosis factor of cortisol release from bovine adrenal zona fasciculata cells through their receptors." Endocrine. 13 (2000): 369-377. Wilson, H.A., J.B. Waldrip, K.H. Nielson, A.M. Judd, S.K. Han, W. Cho, P.J. Sims, J.D. Bell. "Mechanisms by which elevated intracellular calcium induces S49 cell membranes to become susceptible to the action of secretory phospholipase A2." Journal of Biological Chemistry. 274 (1999): 11494-11504. Books Janssen, H.F., Skeen, N.P., Bell, J., and Bradshaw, W. "Improving critical thinking skills in the medical professional with team-based learning." Team-Based Learning for Health Professions Education. Ed. L.K. Michaelsen, D.X. Parmelee, K.K. McMahon, and R.E. Levine. Sterling, Virginia: Stylus Publishing, 2008. |
| Experience |
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General
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| Awards |
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| Courses Taught |
| Biol 120 Science of Biology. Fall and Winter semesters. |