Jason Hansen

Research Interests

One in every 33 live births presents with a birth defect. Unfortunately, the mechanistic origins of the majority these developmental abnormalities remain largely unknown. Interestingly, many of the environmental and chemical insults that promote dysmorhpogenesis are known inducers of oxidative stress, commonly defined as the imbalance of compartmentalized oxidizing and reducing equivalents where the former predominates. Oxidative stress at high levels promotes damage to proteins, DNA and lipids resulting in cell death. Yet at lower levels, oxidative stress can disrupt redox-sensitive cellular signaling, including those that are specific to support normal developmental events, such as proliferation, differentiation and apoptosis. Our laboratory focuses on better understanding the mechanisms of oxidative stress-induced birth defects through various in vivo (animal models) and in vitro (whole embryo culture and stem cell) models. Moreover, we are developing interventions that will serve to protect the developing embryo from oxidative insults and thus, decrease the incidence of birth defects.

Teaching Interests

PDBio 305: Basics of Human Physiology
PDBio 550R: Human Toxicology

Education

• Toxicology, , University of Michigan (2001)
• Zoology, Developmental Biology , Brigham Young University (1997)
• Zoology, Human Biology , Brigham Young University (1994)

Honors and Awards

• Toxicological Sciences Paper of the Year, Society of Toxicology (2017 - 2017)

Memberships

• Society for Redox Biology and Medicine (2016 - Present)

Professional Citizenship

• Editorial Review Board Member, Reproductive Toxicology (2011 - Present)
• Editorial Review Board Member, Journal of Nutritional Biochemistry (2011 - Present)
• Committee/Council Member, Teratology Society (2013 - 2016)
• Committee/Council Chair, Teratology Society (2014 - 2015)

Courses Taught

Show Previous Years

Publications

Micah M Ross Ted B Piorczynski Jamison Harvey Tyson S Burnham Morgan Francis Madison W. Larson Kyle Roe Jason M Hansen Michael R Stark A D Mackay E D Marchant D J Munk Richard Kent Watt Jason Merrell Hansen David Morley Thomson Chad R Hancock T J Rowley, 4th B F Bitner J D Ray D R Lathen A T Smithson B W Dallon C J Plowman Benjamin Thomas Bikman Jason Merrell Hansen M R Dorenkott K M Goodrich L Ye S F O'Keefe A P Neilson Jeffery S Tessem Jason M Hansen Chase J Plowman Ted B Piorczynski Ting Chen Timothy M Moore Mark T Ebbert Natalie L McVey Steven R Madsen David M Hallowell Alex M Harris Ryan P Mackay Robin E Char Chad R Hancock Jason Merrell Hansen John Sai Keong Kauwe David Morley Thomson C Harris J L Jilek K E Sant J Pohl M Reed Jason Merrell Hansen J L Jilek K E Sant K H Cho M S Reed J Pohl Jason Merrell Hansen C Harris Jason Merrell Hansen C Harris C A Easley, 4th J M Bradner A Moser C A Rickman Z T McEachin M M Merritt Jason Merrell Hansen W M Caudle C A Downs L Kreiner X M Zhao P Trac N M Johnson Jason Merrell Hansen L A Brown M N Helms Jason M Hansen W R Hunt S M Zughaier D E Guentert M A Shenep M Koval N A McCarty Jason Merrell Hansen A R Timme-Laragy J V Goldstone B R Imhoff J J Stegeman M E Hahn Jason Merrell Hansen Claudia W Harris D Z Shuster R Roman Gomez K E Sant J Pohl Jason Merrell Hansen A S Kathiria M A Butcher Jason Merrell Hansen A L Theiss Jason Merrell Hansen Craig Harris A M Siore R E Parker C Cuppels N Thorn Jason Merrell Hansen A A Stecenko K L Brigham Craig Harris Jason Merrell Hansen Jason Merrell Hansen Craig Harris Jason Merrell Hansen Jason Merrell Hansen J R Roede Jason Merrell Hansen Y M Go Dean P Jones B R Imhoff Jason Merrell Hansen J Wu Jason Merrell Hansen L Hao R N Taylor N Sidell Lane Fischer A Igoudjil J Magrané Y Li Jason Merrell Hansen G Manfredi J D Glass B R Imhoff Jason Merrell Hansen B R Imhoff Jason Merrell Hansen B R Imhoff Jason Merrell Hansen T E Tipple S E Welty L D Nelin Jason Merrell Hansen Lynette Rogers J M Kleinhenz D J Kleinhenz S You J D Ritzenthaler Jason Merrell Hansen D R Archer R L Sutliff Michael Hart P W Lin L E Myers L Ray S C Song T R Nasr A J Berardinelli K Kundu N Murthy Jason Merrell Hansen A S Neish J D Widder D Fraccarollo P Galuppo Jason Merrell Hansen Dean Jones G Ertl J Bauersachs A L Theiss M Vijay-Kumar T S Obertone Dean Jones Jason Merrell Hansen A T Gewirtz D Merlin S V Sitaraman N Gletsu-Miller Jason Merrell Hansen DeaN Jones Y M Go W E Torres T R Ziegler E Lin James P Lewis R L Messer L Pitts S D Hsu Jason Merrell Hansen J C Wataha J C Wataha Jill Lewis V V McCloud M Shaw Y Omata P E Lockwood R L Messer Jason Merrell Hansen Jason Merrell Hansen S Moriarty-Craige Dean Jones P J Halvey Jason Merrell Hansen J M Johnson Y M Go A Samali Dean Jones Jason Merrell Hansen M Klass Craig Harris M Csete Y M Go T R Ziegler J M Johnson L Gu Jason Merrell Hansen Dean Jones S Ramachandiran Jason Merrell Hansen Dean Jones Jason Richardson G W Miller Jason Merrell Hansen Jason Merrell Hansen H Zhang Dean Jones Jason Merrell Hansen H Zhang Dean Jones Jason Merrell Hansen Y M Go Dean Jones Jason Merrell Hansen W H Watson Dean Jones Jason Merrell Hansen Craig Harris Jason Merrell Hansen S G Gong M Philbert Craig Harris Jason Merrell Hansen K K Harris M A Philbert Craig Harris Jason Merrell Hansen E W Carney Craig Harris

Presentations