Emphasis: Molecular signaling of trophoblast cells during apoptosis; Hypoxia and the regulation of cell invasion during pregnancies complicated with Intrauterine Growth Restriction; Preterm Delivery and Preeclampsia
Emphasis: The study of Neuronal Synaptic Plasticity, and its relevance to Learning and Memory mechanisms, and reward pathways, as well as their relevance to disease states such as Alzheimer’s Disease and Addiction. We employ techniques such as electrophysiology, molecular biology, behavior, immunohistochemistry, optogenetics, etc. to answer questions in these fields
Pre-requisites: None required (better to start early), but Chem 105, Cell 305/363, or Neuro 205 are helpful.
Emphasis: Applying the biology of the tumor microenvironment to the development of liquid biopsy tools to facilitate early cancer diagnoses, regular monitoring of cancer progression, and evaluation of therapy response for timely and accurate interventions.
Emphasis: Understanding the mechanisms of oxidative-induced birth defects through various in vivo and in vitro models. Developing interventions that will protect the developing embryo from oxidative insults.
Emphasis: Gene regulation driving heart formation in the developing embryo. Development and use of computational methods to study gene regulation. Identification of genes underlying congenital heart defects.
Pre-requisites: Contact to discuss; Bioinformatics, Molecular Biology and Developmental Biology projects available. Assignment to a project will depend on student interest and experience.
Emphasis: Using epigenetic marks, bioinformatics, and computational biology to develop novel predictive or diagnostic models for complex diseases with an emphasis on male infertility. Specifically, we specialize in DNA methylation in both somatic cells and sperm and work with a number of local, national, and international clinical partners to identify epigenetic signatures that can aid in clinical decision making.
Emphasis: Membrane Proteins, Paracellular Transport and Barriology, Synthetic Biology, Tissue and Protein Engineering, Development. Use of regeneration animal models. Cancer.
Emphasis: Dr. Parrish's research is focused on the study of epilepsy, including the mechanisms of seizure propagation and termination. He also studies a phenomenon known as cortical spreading depressions, which are associated with both seizure termination and migraines. Finally, he is working to understand the mechanisms of pharmacoresistant, prolonged seizure activity. The lab uses electrophysiology, optogenetics, live network imaging, and computer programming to address our biological questions. https://cell.byu.edu/parrish-lab
Emphasis: Cell and Developmental Biology Subgroup: molecular and cellular interactions that contribute to embryonic development and the most common and debilitating disease conditions. Developmental role of autocrine/paracrine signaling in the lung during branching morphogenesis, pulmonary remodeling induced by interactions between mesenchymal/epithelial compartments, and mechanisms of pulmonary injury and disease related to environmental tobacco or oxidative stress.
Emphasis: Mechanisms that oversee proper development and formation of neural circuits. More specifically 1) Development of neurons that integrate multisensory information, such as auditory, visual and somatosensory inputs, and 2) Development and innervation of mechanosensory hair cells required for sound detection.
Emphasis: Molecular Physiology and Neuroscience focusing on Membrane Biophysics and Neuronal Exocytosis (the release of neurotransmitters that are altered by alcohol, tetanus, and Botox) https://cell.byu.edu/woodbury-lab
Pre-requisites: 1 Semester of Chemistry and 1 Semester of Biology (or equivalent AP courses in High School). Approved lab for Biophysics majors. Other majors are welcome as well.
Approved lab for Biophysics majors. Other majors welcome as well.
Assistant Professor
Room: 3017 LSB eric.melonakos@byu.edu
Emphasis: Using modern neuroscience techniques, such as in vivo calcium imaging, optogenetics, electrophysiology, and computational models, to investigate the origins and functions of synchronous neural activity in rodent models.
Pre-requisites:Approved lab for Biophysics majors. Other majors are welcome as well.